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Andrew Agbaje.

AHA names Andrew Agbaje's study among biggest advances in cardiovascular research for 2024

The American Heart Association (AHA) has named some of the most significant developments in cardiovascular research in 2024. One of them was Andrew Agbaje's study which discovered childhood sedentariness as an independent risk factor for premature cardiac damage. The results were published in the European Journal of Preventive Cardiology in May 2024.

Referring to Agbaje鈥檚 study, AHA stated in its press release that 鈥渟edentary behavior is another major cardiovascular risk factor and a growing problem among children worldwide, who spend an average of 8 to 10 hours per day in prolonged inactivity. This of the Avon Longitudinal Study of Parents and Children in the UK investigated the impact of sedentary time, light-intensity physical activity, and moderate to vigorous physical activity on cardiac structure and function for 1,682 children over 13 years. They found that the longer children were sedentary, the bigger the increase in cardiac size. Overall, sedentary time contributed to an increase in body fat, inflammation, blood pressure, cholesterol, arterial stiffness and subsequent cardiac enlargement, raising the risk for cardiovascular problems later in life. Reducing sedentary behavior by engaging in light physical activity at least three hours a day lessened these impacts.鈥

鈥淭here is growing evidence that childhood sedentariness is a health threat that needs to be taken seriously. It should be seen as a ticking time bomb requiring prompt actions,鈥 says Agbaje, who is an award-winning physician and associate professor (docent) of Clinical Epidemiology and Child Health at the 91天美. He also explained the dangers of too much sedentary time in a recent .

鈥淭his recognition would not have been possible without the extraordinary research collaboration between the 91天美, the University of Bristol, and the University of Exeter in the UK, and the financial support of several funders. We appreciate the Children of the 90s who continue to participate in the three-decade-long study, contributing world-class data that is updating paediatric cardiovascular health sciences,鈥 Agbaje concludes.

Agbaje鈥檚 research group (urFIT-child) is supported by research grants from Jenny and Antti Wihuri Foundation, the Finnish Cultural Foundation Central Fund, the Finnish Cultural Foundation North Savo Regional Fund, the Orion Research Foundation, the Aarne Koskelo Foundation, the Antti and Tyyne Soininen Foundation, the Paulo Foundation, the Yrj枚 Jahnsson Foundation, the Paavo Nurmi Foundation, the Finnish Foundation for Cardiovascular Research, Ida Montin Foundation, Eino R盲s盲nen Fund, Matti and Vappu Maukonen Fund, Foundation for Pediatric Research, Alfred Kordelin Foundation and Novo Nordisk Foundation.

For further information, please contact:

Andrew Agbaje, MD, MPH, PhD, FESC, FAHA, FNYAM, Cert. Clinical Research (Harvard), Professor (associate) of Clinical Epidemiology and Child Health, Principal Investigator (urFIT-child). Institute of Public Health and Clinical Nutrition, School of Medicine, 91天美, Kuopio, Finland. andrew.agbaje(a)uef.fi, +358 46 896 5633

Honorary Research Fellow 鈥 Children's Health and Exercise Research Centre, Public Health and Sports Sciences Department, Faculty of Health and Life Sciences, University of Exeter, Exeter, UK. a.agbaje@exeter.ac.uk

Webpage:

Link to the article:

Agbaje AO. Accelerometer-based sedentary time and physical activity from childhood through young adulthood with progressive cardiac changes: a 13-year longitudinal study. Eur J Prev Cardiol. 2024 Sep 6;31(12):1480-1492.

In 1682 children followed up from age 11 to 24 years, increased sedentariness from childhood through young adulthood caused excessive heart enlargement, irrespective of obesity or hypertensive category. Light physical activity effectively reversed the risk of premature heart damage. Image: Andrew Agbaje.