- Health and well-being
- Event date:
-
- Time:
- 15:00鈥16:00
- Event location:
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Kuopio campus, Snellmania building, room SN201
- Additional information:
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Yliopistonranta 8
- Add to calendar:
Outlook
Seminars in Health Sciences continues with a lecture by Group leader from University of Oslo and University of Helsinki.
The seminar is titled: Finding cues in the tumor microenvironment for pancreatic cancer chemosensitivity.
Dr. Biswa Sahu obtained his PhD with distinction from the Faculty of Medicine at the University of Helsinki, Finland, studying enhancer reprogramming in prostate cancer. He then pursued postdoctoral training with Professor Jussi Taipale at the University of Helsinki, Finland, and the University of Cambridge, UK, from 2013 to 2018. During this time, he developed a new human cell transformation approach and several novel designs to study the sequence determinants of human gene regulatory elements from completely random sequences using massively parallel reporter assays. Dr. Sahu has led his own research group since 2019 at the Faculty of Medicine, University of Helsinki. In 2022, he was recruited as a group leader in precision medicine to the Centre for Molecular Biosciences and Medicine Norway (NCMBM), an EMBL partner institute at the University of Oslo.
Dr. Sahu鈥檚 research focuses on the epigenetic plasticity of human cancer, with a particular emphasis on the non-coding regulatory genome, enhancer reprogramming, and how transposable elements contribute to cancer-specific gene regulatory circuits through enhancer hijacking. His group also investigates how transcription factors utilize these gene regulatory elements to control cell fate decisions and how non-genetic transcriptional mechanisms drive cancer initiation and treatment resistance. Dr. Sahu鈥檚 group employs state-of-the-art experimental and computational methods to generate and integrate data using genome-wide multi-omics technologies at bulk and single cell resolution from patient material and various cellular and organoid models for understanding fundamental mechanisms of transcriptional regulation as well as enhanceropathies such as cancer.
The seminar is organized by the UEF Faculty of Health Sciences, and it is open to everyone interested.
For further information, please contact organisers by email: dpmm@uef.fi.